Bioactivity:Meclinertant is an effective, selective, nonpeptide, and orally active neurotensin receptor 1 (NTS1) antagonist. Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization (pA2 : 8.13), in human colon carcinoma (HT-29) cell
CAS Nr:
146362-70-1
Purity:
98%
SMILES:
O=C(C1=NN(C2=CC=NC3=C2C=CC(Cl)=C3)C(C4=C(C=CC=C4OC)OC)=C1)NC5([C@H]6C[C@H](C7)C[C@@H]5C[C@H]7C6)C(O)=O
Formula:
C32H31ClN4O5
Molecular weight:
587,07
Pathway:
Others
Target:
Others